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Home - Products - Chromatin/Epigenetic - COX - (S)-( )-Ibuprofen

(S)-( )-Ibuprofen

CAS No. 51146-56-6

(S)-( )-Ibuprofen ( S)-Ibuprofen )

Catalog No. M14764 CAS No. 51146-56-6

An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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1G 33 In Stock
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Biological Information

  • Product Name
    (S)-( )-Ibuprofen
  • Note
    Research use only, not for human use.
  • Brief Description
    An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form.
  • Description
    An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form; also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50=62 and 122 uM, respectively).
  • Synonyms
    S)-Ibuprofen
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    Bcl-2;COX;Cysticfibrosistransmembraneconductanceregulator;PPARγ;thrombomodulin
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    51146-56-6
  • Formula Weight
    206.28
  • Molecular Formula
    C13H18O2
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: 1 mg/mL (Need ultrasonic and warming); DMSO: < 0.1 mg/mL
  • SMILES
    C[C@@H](C1=CC=C(C=C1)CC(C)C)C(=O)O
  • Chemical Name
    Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-,(αS)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Evans AM, et al. Br J Clin Pharmacol. 1991 Feb;31(2):131-8.
2. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.
3. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.
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