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(S)-( )-Ibuprofen
CAS No. 51146-56-6
(S)-( )-Ibuprofen ( S)-Ibuprofen )
Catalog No. M14764 CAS No. 51146-56-6
An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1G | 33 | In Stock |
|
Biological Information
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Product Name(S)-( )-Ibuprofen
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NoteResearch use only, not for human use.
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Brief DescriptionAn enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form.
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DescriptionAn enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form; also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50=62 and 122 uM, respectively).
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SynonymsS)-Ibuprofen
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorBcl-2;COX;Cysticfibrosistransmembraneconductanceregulator;PPARγ;thrombomodulin
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number51146-56-6
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Formula Weight206.28
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Molecular FormulaC13H18O2
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Purity>98% (HPLC)
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SolubilityH2O: 1 mg/mL (Need ultrasonic and warming); DMSO: < 0.1 mg/mL
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SMILESC[C@@H](C1=CC=C(C=C1)CC(C)C)C(=O)O
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Chemical NameBenzeneacetic acid, α-methyl-4-(2-methylpropyl)-,(αS)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Evans AM, et al. Br J Clin Pharmacol. 1991 Feb;31(2):131-8.
2. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.
3. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.
2. Villanueva M, et al. Br J Clin Pharmacol. 1993 Mar;35(3):235-42.
3. Scheuren N, et al. Br J Pharmacol. 1998 Feb;123(4):645-52.
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